{"id":2898,"date":"2024-11-13T13:13:47","date_gmt":"2024-11-13T12:13:47","guid":{"rendered":"https:\/\/www.ceprasrl.it\/sectors\/laboratory\/chemicals-compliance\/clp\/test-tossicologici\/"},"modified":"2024-11-27T16:51:07","modified_gmt":"2024-11-27T15:51:07","slug":"toxicological-test","status":"publish","type":"page","link":"https:\/\/www.ceprasrl.it\/en\/sectors\/laboratory\/chemicals-compliance\/clp\/toxicological-test\/","title":{"rendered":"Toxicological test"},"content":{"rendered":"

CEPRA proposes TOXICOLOGICAL TEST according to GLP (Good Lab Practice) as required by REACH Regulation 1907\/2006 or by GHS.<\/p>\n

Thanks to a national and international labs, CEPRA support the company to choose best testing strategy, the best lab and to evaluate results of studies.<\/p>\n

Principal TOXICOLOGICAL TEST \/ STUDIES:<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

Study<\/strong><\/h3>\n<\/td>\n

\n

Guideline<\/strong><\/h3>\n<\/td>\n<\/tr>\n

Skin irritation \/ corrosion (in vitro)<\/td>\nOECD 431 – OECD 439<\/td>\n<\/tr>\n
Eye irritation \/ corrosion (in vitro)<\/td>\nOECD 437 – OECD 492<\/td>\n<\/tr>\n
Skin sensitization
\n– Local Lymph Node Assay
\n– Magnusson \/ Kligman
\n– Buehler method<\/td>\n		OECD 429
\nOECD 406, EEC B.6
\nOECD 406<\/td>\n<\/tr>\n
Bacterial reverse mutation test (Ames-test)<\/td>\nOECD 471- EEC B.13\/ 14<\/td>\n<\/tr>\n
Cytogenetic testing in mammalian cells:
\nChromosome Aberration Test (in vitro)<\/td>\n		OECD 473
\nEEC B.10<\/td>\n<\/tr>\n
Micronucleus test (in vitro)<\/td>\nOECD 487
\nEEC B.10<\/td>\n<\/tr>\n
Gene mutation test in mammalian cells:
\nMouse Lymphoma Assay (in vitro)<\/td>\n		OECD 476
\nEEC B.17<\/td>\n<\/tr>\n
Acute oral toxicity
\n– Acute Toxic Class Method \u201cATC\u201d
\n– Fixed dose procedure
\n– Up and down procedure<\/td>\n		OECD 423
\nOECD 420
\nOECD 425<\/td>\n<\/tr>\n
Acute inhalation toxicity<\/td>\nOECD 403<\/td>\n<\/tr>\n
Acute dermal toxicity<\/td>\nOECD 402, OECD 434
\nEEC B.3<\/td>\n<\/tr>\n
Repeated dose toxicity<\/td>\nOECD 40 -EEC B.7
\nOECD 410
\nOECD 412
\nOECD 408 – EEC B.26
\nOECD 411
\nOECD 413
\nOECD 452<\/td>\n<\/tr>\n
Assessment of the toxicokinetic behaviour<\/td>\nOECD 417<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

CEPRA proposes TOXICOLOGICAL TEST according to GLP (Good Lab Practice) as required by REACH Regulation 1907\/2006 or by GHS. Thanks to a national and international labs, CEPRA support the company to choose best testing strategy, the best lab and to evaluate results of studies. Principal TOXICOLOGICAL TEST \/ STUDIES: Study Guideline Skin irritation \/ corrosion […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":2889,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-2898","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.ceprasrl.it\/en\/wp-json\/wp\/v2\/pages\/2898","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ceprasrl.it\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ceprasrl.it\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ceprasrl.it\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ceprasrl.it\/en\/wp-json\/wp\/v2\/comments?post=2898"}],"version-history":[{"count":0,"href":"https:\/\/www.ceprasrl.it\/en\/wp-json\/wp\/v2\/pages\/2898\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.ceprasrl.it\/en\/wp-json\/wp\/v2\/pages\/2889"}],"wp:attachment":[{"href":"https:\/\/www.ceprasrl.it\/en\/wp-json\/wp\/v2\/media?parent=2898"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}