{"id":3011,"date":"2024-11-13T17:19:30","date_gmt":"2024-11-13T16:19:30","guid":{"rendered":"https:\/\/www.ceprasrl.it\/sectors\/laboratory\/chemicals-compliance\/reach\/test-tossicologici\/"},"modified":"2024-11-28T13:08:28","modified_gmt":"2024-11-28T12:08:28","slug":"toxicological-test","status":"publish","type":"page","link":"https:\/\/www.ceprasrl.it\/en\/sectors\/laboratory\/chemicals-compliance\/reach\/toxicological-test\/","title":{"rendered":"Toxicological Test"},"content":{"rendered":"<p>CEPRA proposes TOXICOLOGICAL TEST according to GLP (Good Lab Practice) as required by REACH Regulation 1907\/2006 or by GHS<\/p>\n<p>Thanks to a national and international labs, CEPRA support the company to choose best testing strategy, the best lab and to evaluate results of studies<\/p>\n<p>Principal TOXICOLOGICAL TEST \/ STUDIES:<\/p>\n<table border=\"1\" cellspacing=\"1\" cellpadding=\"1\">\n<tbody>\n<tr>\n<td>\n<h3>ANNEX<\/h3>\n<\/td>\n<td>\n<h3>Number<\/h3>\n<\/td>\n<td>\n<h3>STUDY<\/h3>\n<\/td>\n<td>\n<h3>GUIDELINE<\/h3>\n<\/td>\n<\/tr>\n<tr>\n<td>VII<\/td>\n<td>8.1<\/td>\n<td>Skin irritation \/ corrosion (in vitro)<\/td>\n<td>OECD 431 &#8211; OECD 439<\/td>\n<\/tr>\n<tr>\n<td>VII<\/td>\n<td>8.2<\/td>\n<td>Eye irritation \/ corrosion (in vitro)<\/td>\n<td>OECD 437 &#8211; OECD 492<\/td>\n<\/tr>\n<tr>\n<td>VII<\/td>\n<td>8.3<\/td>\n<td>Skin sensitization<\/td>\n<td>OECD 429<br \/>\nOECD 406, EEC B.6<br \/>\nOECD 442<\/td>\n<\/tr>\n<tr>\n<td>VII<\/td>\n<td>8.4.1<\/td>\n<td>Bacterial reverse mutation test (Ames-test)<\/td>\n<td>OECD 471- EEC B.13\/ 14<\/td>\n<\/tr>\n<tr>\n<td>VIII<\/td>\n<td>8.4.2<\/td>\n<td>Cytogenetic testing in mammalian cells:<br \/>\nChromosome Aberration Test (in vitro)<\/td>\n<td>OECD 473<br \/>\nEEC B.10<\/td>\n<\/tr>\n<tr>\n<td>VIII<\/td>\n<td>8.4.2<\/td>\n<td>Micronucleus test (in vitro)<\/td>\n<td>OECD 487<br \/>\nEEC B.10<\/td>\n<\/tr>\n<tr>\n<td>VIII<\/td>\n<td>8.4.3<\/td>\n<td>Gene mutation test in mammalian cells:<br \/>\nMouse Lymphoma Assay (in vitro)<\/td>\n<td>OECD 476<br \/>\nEEC B.17<\/td>\n<\/tr>\n<tr>\n<td>VII<\/td>\n<td>8.5.1<\/td>\n<td>Acute oral toxicity<br \/>\n&#8211; Acute Toxic Class Method \u201cATC\u201d<br \/>\n&#8211; Fixed dose procedure<br \/>\n&#8211; Up and down procedure<\/td>\n<td>OECD 423<br \/>\nOECD 420<br \/>\nOECD 425<\/td>\n<\/tr>\n<tr>\n<td>VIII<\/td>\n<td>8.5.2<\/td>\n<td>Acute inhalation toxicity<\/td>\n<td>OECD 403<\/td>\n<\/tr>\n<tr>\n<td>VIII<\/td>\n<td>8.5.3<\/td>\n<td>Acute dermal toxicity<\/td>\n<td>OECD 402, OECD 434<br \/>\nEEC B.3<\/td>\n<\/tr>\n<tr>\n<td><\/td>\n<td><\/td>\n<td>Repeated dose toxicity<\/td>\n<td>OECD 40 -EEC B.7<br \/>\nOECD 410<br \/>\nOECD 412<br \/>\nOECD 408 &#8211; EEC B.26<br \/>\nOECD 411<br \/>\nOECD 413<br \/>\nOECD 452<\/td>\n<\/tr>\n<tr>\n<td>VIII<\/td>\n<td>8.8.1<\/td>\n<td>Assessment of the toxicokinetic behaviour<\/td>\n<td>OECD 417<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>CEPRA proposes TOXICOLOGICAL TEST according to GLP (Good Lab Practice) as required by REACH Regulation 1907\/2006 or by GHS Thanks to a national and international labs, CEPRA support the company to choose best testing strategy, the best lab and to evaluate results of studies Principal TOXICOLOGICAL TEST \/ STUDIES: ANNEX Number STUDY GUIDELINE VII 8.1 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":2997,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-3011","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.ceprasrl.it\/en\/wp-json\/wp\/v2\/pages\/3011","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ceprasrl.it\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ceprasrl.it\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ceprasrl.it\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ceprasrl.it\/en\/wp-json\/wp\/v2\/comments?post=3011"}],"version-history":[{"count":0,"href":"https:\/\/www.ceprasrl.it\/en\/wp-json\/wp\/v2\/pages\/3011\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.ceprasrl.it\/en\/wp-json\/wp\/v2\/pages\/2997"}],"wp:attachment":[{"href":"https:\/\/www.ceprasrl.it\/en\/wp-json\/wp\/v2\/media?parent=3011"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}